https://nova.newcastle.edu.au/vital/access/ /manager/Index ${session.getAttribute("locale")} 5 Intensive care unit randomised trial comparing two approaches to oxygen therapy (ICU-ROX): results of the pilot phase https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:32716 Wed 18 Jul 2018 16:33:36 AEST ]]> Education on invasive mechanical ventilation involving intensive care nurses: a systematic review https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:44087 Wed 13 Mar 2024 11:24:55 AEDT ]]> Being in limbo: the experience of critical illness in intensive care and beyond https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:15298 Wed 11 Apr 2018 15:43:38 AEST ]]> Long term outcomes following hospital admission for sepsis using relative survival analysis: a prospective cohort study of 1,092 patients with 5 year follow up https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:19506 Wed 11 Apr 2018 11:23:39 AEST ]]> Incidence of contrast-induced nephropathy in intensive care patients undergoing computerised tomography and prevalence of risk factors https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:7635 Wed 11 Apr 2018 11:03:32 AEST ]]> Phenomenological inquiry as a methodology for investigating the lived experience of being critically ill in intensive care https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:29012 Wed 11 Apr 2018 09:36:20 AEST ]]> Implications for research and practice of the biographic approach for storytelling https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:34066 Wed 06 Feb 2019 09:50:57 AEDT ]]> Intensive care unit outcomes in patients with hematological malignancy https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:54064 55%) and prognosis >12 months (based on disease-specific risk scores) were significantly associated with overall survival (P = 0.024 and P = 0.001). Induction and posttransplantation therapy were predictive of poor ICU survival outcome (P < 0.0001 and P = 0.041). APACHE scores were significant predictors of ICU mortality (P = 0.002 for APACHE II and P < 0.0001 for APACHE III). Conclusion: Survival outcomes for patients with hematological malignancy admitted to the ICU correlate with functional and comorbidity status. Disease-specific prognostic scores can assist in recognizing patients likely to benefit from ICU admission.]]> Tue 30 Jan 2024 13:58:21 AEDT ]]> Compliance phenotypes in early acute respiratory distress syndrome before the COVID-19 pandemic https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:41102 Tue 26 Jul 2022 14:20:11 AEST ]]> Relative hypotension and adverse kidney-related outcomes among critically ill patients with shock a multicenter, prospective cohort study https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:42296 20% as key exposure variables. New significant AKI was defined as an AKI-stage increase of two or more (Kidney Disease: Improving Global Outcome creatinine-based criteria). Measurements and Main Results: The median MPP deficit was 19% (interquartile range, 13–25), and 54% (interquartile range, 19–82) of time points were spent with an MPP deficit > 20%. Seventy-three (24%) patients developed new significant AKI; 86 (29%) patients developed MAKE. For every percentage increase in the time-weighted average MPP deficit, multivariable-adjusted odds of developing new significant AKI and MAKE increased by 5.6% (95% confidence interval, 2.2–9.1; P = 0.001) and 5.9% (95% confidence interval, 2.2–9.8; P = 0.002), respectively. Likewise, for every one-unit increase in the percentage of time points with an MPP deficit > 20%, multivariable-adjusted odds of developing new significant AKI and MAKE increased by 1.2% (0.3–2.2; P = 0.008) and 1.4% (0.4–2.4; P = 0.004), respectively. Conclusions: Vasopressor-treated patients with shock are often exposed to a significant degree and duration of relative hypotension, which is associated with new-onset, adverse kidney-related outcomes.Study registered with Australian New Zealand Clinical Trial Registry (ACTRN 12613001368729).]]> Tue 21 Mar 2023 18:30:16 AEDT ]]> Conservative oxygen therapy for mechanically ventilated adults with sepsis: a post hoc analysis of data from the intensive care unit randomized trial comparing two approaches to oxygen therapy (ICU-ROX) https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:38898 2 ≥ 97% (23.5 h [interquartile range (IQR) 8–70] vs. 47 h [IQR 11–93], absolute difference, 23 h; 95% CI 8–38), and more time receiving an FiO₂ of 0.21 than patients allocated to usual oxygen therapy (20.5 h [IQR 1–79] vs. 0 h [IQR 0–10], absolute difference, 20 h; 95% CI 14–26). At 90-days, 47 of 130 patients (36.2%) assigned to conservative oxygen and 35 of 120 patients (29.2%) assigned to usual oxygen had died (absolute difference, 7 percentage points; 95% CI − 4.6 to 18.6% points; P = 0.24; interaction P = 0.35 for sepsis vs. non-sepsis). There were no statistically significant differences between groups for secondary outcomes but point estimates of treatment effects consistently favored usual oxygen therapy. Conclusions: Point estimates for the treatment effect of conservative oxygen therapy on 90-day mortality raise the possibility of clinically important harm with this intervention in patients with sepsis; however, our post hoc analysis was not powered to detect the effects suggested and our data do not exclude clinically important benefit or harm from conservative oxygen therapy in this patient group. Clinical Trials Registry: ICU-ROX Australian and New Zealand Clinical Trials Registry number ACTRN12615000957594.]]> Tue 01 Mar 2022 15:43:40 AEDT ]]> Review of the Australian Incident Monitoring System https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:587 Thu 25 Jul 2013 09:10:29 AEST ]]> Aspiration pneumonitis in an overdose population: frequency, predictors, and outcomes https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:1489 24 hrs [odds ratio, 4.42; 95% confidence interval, 2.42-8.10]). The mortality for patients with aspiration pneumonitis was 8.5% compared with 0.4% for those without (odds ratio, 23; 95% confidence interval, 9-60; p < .0001), and they had a significantly higher intensive care unit admission rate. The median length of stay of patients with aspiration pneumonitis was 126 hrs (interquartile range, 62-210 hrs) compared with 14.7 hrs (interquartile range, 7-23 hrs) in patients without (p < .0001). Conclusions: Our study has shown a number of risk factors in overdose patients that are associated with aspiration pneumonitis that may allow the early identification of these patients for appropriate observation and management. Patients with aspiration pneumonitis have a significantly increased mortality and length of stay in the hospital.]]> Sat 24 Mar 2018 08:28:05 AEDT ]]> Role of paediatric intensive care following adenotonsillectomy for severe obstructive sleep apnoea: criteria for elective admission https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:17401 Sat 24 Mar 2018 08:01:28 AEDT ]]> The experience of sleep deprivation in intensive care patients: Findings from a larger hermeneutic phenomenological study https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:18542 Sat 24 Mar 2018 07:50:17 AEDT ]]> The umbilical arterial catheter: a formula for improved positioning in the very low birth weight infant https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:5186 Sat 24 Mar 2018 07:47:48 AEDT ]]> Cautionary tales from the neonatal intensive care unit: diapers may mislead urinary output estimation in extremely low birthweight infants https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:5510 Sat 24 Mar 2018 07:46:39 AEDT ]]> The experience of communication difficulties in critically ill patients in and beyond intensive care: findings from a larger phenomenological study https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:27060 Sat 24 Mar 2018 07:25:21 AEDT ]]> A multicenter randomized trial of continuous versus intermittent β-lactam infusion in severe sepsis https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:24441 Sat 24 Mar 2018 07:17:27 AEDT ]]> Education of ICU nurses regarding invasive mechanical ventilation: findings from a cross-sectional survey https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:22577 Sat 24 Mar 2018 07:15:56 AEDT ]]> The complications of opioid use during and post–intensive care admission: A narrative review https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:48244 Sat 11 Mar 2023 12:50:37 AEDT ]]> Intensive care nurses’ perceptions of the continuing education regarding mechanical ventilation at a major regional tertiary-referral hospital in Australia https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:33447 Mon 23 Sep 2019 13:51:40 AEST ]]> Critical care nurses’ knowledge and attitudes toward pressure injury prevention: A pre and post intervention study https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:52533 Mon 16 Oct 2023 14:50:19 AEDT ]]> Standard care versus individualized blood pressure targets among critically ill patients with shock: A multicenter feasibility and preliminary efficacy study https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:46976 Mon 12 Dec 2022 16:54:26 AEDT ]]> An exploratory international survey of the assessments and interventions used by occupational therapists and physiotherapists during the hospitalization of people with Guillain-Barré syndrome https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:52787 Fri 27 Oct 2023 09:47:40 AEDT ]]> Survivors of Acute Lung Injury Have Greater Impairments in Strength and Exercise Capacity Than Survivors of Other Critical Illnesses as Measured Shortly After ICU Discharge https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:44494 Fri 14 Oct 2022 09:04:40 AEDT ]]> Barriers to nurse-led pain management for adult patients in intensive care units: An integrative review https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:53593 Fri 08 Dec 2023 15:53:13 AEDT ]]>